TCI Building Blocks for Organic Semiconductor
Light and flexible organic semiconductor materials are promising for foldable electronic circuits1) and implantable biometric sensors,2) although such electronic devices are hardly obtained from silicon-based semiconductors. We have developed a printed electronics system giving large scale and highly precise devices on flexible substrates (eg. paper and film) by a printing method thanks to the solubility of organic materials. The printing method is one efficient technology for mass production and low cost production of semiconducting devices.3) Organic photovoltaics (OPV) is a photoelectric conversion device using organic semiconductors. Organic light-emitting diode (OLED) devices have received much attention, because they are expected to be a next generation display and light source, thanks to lightweight and flexible organic semiconductor materials. Organic semiconductor materials are mainly classified into small molecular and polymer types, and an oligomer type is a middle class between them.
TCI Fluorinating Agents, Building Blocks, Fluorinated Bioactive Compounds
The introduction of fluorine into bioactive molecules often results in significant changes in their chemical, physical, and biological properties. Fluorine uniquely affects the property of organic molecules due to the fluorine atom’s blocking effect in metabolic transformations and mimicking of enzyme substrates, and then increases the molecular lipophilicity to enhance bioavailability. Approximately 30% of all agrochemicals and 20% of all pharmaceuticals contain fluorine.1) HMG-CoA reductase inhibitor fluorostatin (atorvastatin), antibiotic fluoroquinolone (levofloxacin), and antitumor fluoronucleoside (tegafur) are successful examples of the introduction of fluorine into organic molecules (Fig. 1). Therefore, fluorinating agents are useful tools for the synthesis of pharmaceutical and agricultural compounds.
Since there are few naturally occurring fluorine containing compounds, it is necessary to fluorinate organic compounds at a certain stage of the syntheses. Though fluorine gas and hydrogen fluoride are used as fluorine sources, they are very toxic and corrosive and require special equipment and techniques for handling them. Therefore, alternate fluorinating agents have been developed, which are used in laboratories to easily introduce a fluorine atom at selected positions of the compounds. The fluorinating agents are roughly classified into two categories: nucleophilic and electrophilic. Nucleophilic fluorinating agents are those where the fluoride anion serves as a reaction active species. Electrophilic fluorinating agents are those where the electron-deficient fluorine atom serves as a reaction active species. In addition, a fluorinated building block is used as a fluorine source, which has both a fluorine atom and a replaceable functional group in a molecule.
TCI Cosmetic Materials
In the never ending search to improve and retain their youthful appearance, more and more people are turning to cosmetic applications for their skin. In an effort to keep their skin healthy, as well as cover up blemishes and wrinkles, more people are seeking cosmetic products which contain moisturizers, whitening agents, and sunscreens. Below are listed some high quality products available from us for use in cosmetics.
TCI Chemical Compounds Purified by Sublimation
Reagent purity is paramount in countless applications, and is of particular importance when involving electronic materials including polyaromatic hydrocarbons. Pentacene (P0030, P2524) and N,N’-diphenyl-N,N’-di(m-tolyl)-benzidine (D3236) in particular have garnered increased interest for their applications in organic semiconducting materials. The purification of organic compounds is almost entirely conducted via column chromatography or recrystallization. These mainstay procedures are highly effective, but are limited to compounds soluble in organic solvents.
Many electronic materials including PAHs due to their extensive π conjugation and aromaticity are poorly or completely insoluble in organic solvents. Fortunately, this very π conjugation lends to both high volatility with a relatively high sublimation temperature lending to sublimation purification being a highly effective purification avenue. To address research and industry demands, TCI has introduced several electronic materials purified by sublimation which can be readily and reliably used in a variety of research applications.
TCI C-H Bond Activation Reaction
Recently, there have been a large number of reports on “C-H bond activation reaction”. C-H bond activation is a methodology for directly forming carbon-carbon bonds by activating a carbonhydrogen bond, which is the most fundamental linkage in organic chemistry. Traditional cross coupling reactions have been one of the most useful synthetic methods for the formation of carboncarbon bonds. However, the cross coupling reaction requires extra procedures for preparing organic halides (or triflates) compounds, and organic boron or metal compounds. On the other hand, the C-H bond activation can reduce these procedures, thus making this reaction a cost-effective and ecofriendly system.
Other Products Available from Greyhound
If you know our company you will know that for over 38 years Greyhound has been supplying high quality Chromatography consumables to laboratories around the world. We hold ISO 9001:2008 Certificate No: RS 30332 for the supply and stockholding of analytical reference standards, chemicals, chromatography columns and related accessories. Our Certified Reference Standards are supplied by Guide 34 accredited manufacturers.
If you don’t know us, please visit our website www.greyhoundchrom.com we have access to over 1 million products – including the largest catalogue of Certified Reference and Analytical standards in the world.
Greyhound’s extensive range covers all areas of Agriculture, Chemical, Environmental, Food, Forensics, Petrochemical, Chemical, Life Sciences and Pharmaceutical analysis, holding stock of many popular products for prompt delivery via our extensive logistics network.
Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. With state-of-the art facilities and highly trained staff, Greyhound provides technical advice and distribution of Chromatography consumables across all disciplines. Our service is designed to provide a wide range of products, to help our clients to achieve excellent, cost-effective results. Greyhound manufactures its own range of Capillary Columns, Syringe Filters, SPE Columns and HPLC Columns, the 'Q' Range, as well as representing the industry’s best known manufacturers.
By working with the industry’s best known manufacturers we are able to tailor products to customer requirements and supply products on behalf of 3M, Biosolve; Chiron; Chromacol; Chem Service (Environmental and Pesticides); EP Scientific; Extrasynthese, Hach Lange, Hamilton; High Purity Standards; Jour Research; Larodan Fine Chemicals; Macherey-Nagel; Millipore, National Scientific; NIST, PAH Reference Standards; Pfaltz and Bauer; Regis Technologies; Rheodyne; RT Corporation; Samco Scientific; SGE; SGT Filters; Sigma Aldrich, Fluka and Supelco, Sillicycle, Speciality Gases, Swagelok, TCI, Thermo, Upchurch; Valco, Vici , Wellington Laboratories and Wheaton. We offer a full range of chromatography and laboratory consumables, if you visit our website and do not see what you require please contact us and we will do our best to source your requirements for you.
Our services include; Chemical Standards; Chiral Chromatography; Derivatives Analysis; Solvents; Dioxins/Furans/PCBs/PBDEs; Environmental Analysis; Gas Filters; GC; GC-MS; LC-MS; HPLC; ICP, ICP-MS, AA; Ion Chromatography; Lamps; Prep Silica; Reagents; SPE Solid Phase Extraction; SPME Solid Phase Micro-Extraction; Syringes; TLC Thin Layer Chromatography; Valves; Vials/Caps/Septa. Our sales team is available to discuss your requirements in detail, from the application of products, to sourcing and prompt delivery. We are able to source hard to find chemicals which are no longer commercially available and are able to supply over 13,000 laboratory chemicals in small, convenient units.
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About the Author
Susan Massie, Sales & Marketing Director, Greyhound Chromatography and Allied Chemicals Email: sue@greyhoundchrom.com
Susan Massie is the Sales & Marketing Director for Greyhound Chromatography and Allied Chemicals, affectionately known as 'Greyhound' in our scientific community. Greyhound was founded by Susan's husband Paul Massie more than 40 years ago, Susan hasn't been in the business for all of that time but has been involved with Greyhound for over 19 years. Greyhound continues to grow, expanding into new markets and taking on the challenges of our ever changing environment. It's heartwarming to witness the world waking up to the fact that we are damaging our planet on a daily basis. Every action we take has a direct effect on our planet and the world we leave behind for future generations. Susan is passionate about climate change and is happy to work in an industry that can have a direct effect on reducing the impact of our actions on the environment. All of the team at Greyhound take our responsibilities very seriously, the products that we supply are used by the world's leading scientists and chemists as they endeavour to monitor and repair the environment. All is not lost, if we all take responsibility for our actions, from reducing our waste and reusing or recycling our material collateral we can make a difference. The internet is full of useful advice and guidance, Susan is proud to contribute to that wealth of knowledge whenever she can.
Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. Greyhound provides technical advice and distribution of Certified Reference Standards and Materials, Laboratory Consumables, Solvents and Reagents across all scientific disciplines. Greyhound Chromatography offers over 1 Million products from its UK warehouse. The team at Greyhound are proud to support the work of the world's leading scientists and chemists as they challenge the abuse of our planet and try to make a difference to the world we leave behind for our ancestors.
You can view Susan's Linked In Profile here https://www.linkedin.com/in/susan-massie-79ab4121/