Hamilton PRP-X500 is a superficially porous polymeric
anion exchange column.
The methacrylate
polymeric coating of the PRP-X500 provides
a more hydrophilic surface, preventing
hydrophobic interaction sample losses typically
seen on other commercially available protein
HPLC columns.
Recovery of sample is excellent
with PRP-X500 and the support’s limited
permeability prevents proteins from entering
the pores and unfolding, which causes peak
ghosting. The superficially porous properties of
the packing material improves mass-transfer,
shortening the diffusion path of the analyte.
This results in shortened run times, improved
resolution, and sharp sample bands.
Pore Size: Superficially porous
Exchange Capacity: 1.6 meq/gm
Material: Methacrylamido propyl trimethyl
ammonium chloride (SAX)
Applications: Proteins, peptides, and DNA/RNA