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Choosing the best solvents for Mass Spectrometry| Greyhound Chromatography

How to reduce Mass Spectrometer Downtime 0.1µm Filtered Solvents from Greyhound Chromatography are the Answer

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Reduction of Mass Spectrometer downtime is an issue that concerns many research scientists today.  Recent improvements on the High and Ultra PLC instruments coupled with MS, PDA, ELSD, CAD etc detectors have led to special high-performing systems.  Ultra low detection limits and valid analysis of molecular structures of proteins, peptides, oligonucleotides and other chemicals brought these new techniques a growing popularity, especially in the pharmaceutical and bio-technology industry.

Faster analysis is often negated by long periods of inactivity because of problems clearing tubes that have become clogged due to impurities in the solvents.  Today's UPLC equipment is very sensitive and the choice of the purest solvent is essential.   UHPLC is fast becoming an established technique.  Hardware and column improvements allow higher temperature and pressure separations, improving resolution and speed.  For these improvements to provide a cost saving to the laboratory there needs to be a minimum of disruption caused by instrument downtime.

 Full Range of Analytical Solvents available from Biosolve HERE                                                                                 


Working closely with Waters Corporation, Greyhound Chromatography provides Maintenance Solvent Kits for the Mass Spectrometry Instruments that they are installing. The kit consists of ULC/MS Grade Water, Acetonitrile, Methanol, 2-Propanol and Formic Acid. The solvents are manufactured by Biosolve, Greyhound distribute their products worldwide from the UK. Greyhound also works with other leading instrument manufacturers and are able to provide kits of any combination of solvents to suit individual needs.

Biosolve ULC/MS solvents and formulations are micro filtered at 0.1µm and have a very low residue on evaporation, offering the best protection for your columns and detectors. All Biosolve ULC/MS reagents are packaged under inert gas, for improved shelf life. Our customers are reporting to us that by using these highly filtered solvents, instrument down time has been dramatically reduced. So much so, Waters Assoc. are recommending the Biosolve range to their customers as their use has greatly improved the efficiency of their machines.

The range of Biosolve solvents are particularly suited to the pharmaceutical and bio-technology industry as they have high chemical purity, high UV transmission, lowest peak impurities and drift in the gradient elution tests to ensure reproducibility. Low fluorescence impurities and low level of ionic background of less than 100 ppb of Alkali metal.

 

Please visit our website at www.greyhoundchrom.com/Accessories/Solvents or use the link below to take you straight there. http://www.greyhoundchrom.com/category/178-solvents.aspx

Technical Data Sheets and MSDS are available via our website for each Biosolve product.

You will see on our website that we offer a wide range of Chromatography and Laboratory consumables including Analytical Reference Standards, Solvents and Reagents, we are able to ship worldwide. Please let us know if we can be of any assistance to you.

We would be happy to discuss pricing, including contract rates for bulk supply and supply of kits or individual products .

 

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About the Author

Susan MAssie, Marketing Director Greyhound Chromatography Image

Susan Massie, Sales & Marketing Director, Greyhound Chromatography and Allied Chemicals Email: sue@greyhoundchrom.com

Susan Massie is the Sales & Marketing Director for Greyhound Chromatography and Allied Chemicals, affectionately known as 'Greyhound' in our scientific community. Greyhound was founded by Susan's husband Paul Massie more than 40 years ago, Susan hasn't been in the business for all of that time but has been involved with Greyhound for over 17 years. Greyhound continues to grow, expanding into new markets and taking on the challenges of our ever changing environment. It's heartwarming to witness the world waking up to the fact that we are damaging our planet on a daily basis. Every action we take has a direct effect on our planet and the world we leave behind for future generations. Susan is passionate about climate change and is happy to work in an industry that can have a direct effect on reducing the impact of our actions on the environment. All of the team at Greyhound take our responsibilities very seriously, the products that we supply are used by the world's leading scientists and chemists as they endeavour to monitor and repair the environment. All is not lost, if we all take responsibility for our actions, from reducing our waste and reusing or recycling our material collateral we can make a difference. The internet is full of useful advice and guidance, Susan is proud to contribute to that wealth of knowledge whenever she can.

Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. Greyhound provides technical advice and distribution of Certified Reference Standards and Materials, Laboratory Consumables, Solvents and Reagents across all scientific disciplines. Greyhound Chromatography offers over 1 Million products from its UK warehouse. The team at Greyhound are proud to support the work of the world's leading scientists and chemists as they challenge the abuse of our planet and try to make a difference to the world we leave behind for our ancestors.

You can view Susan's Linked In Profile here https://www.linkedin.com/in/susan-massie-79ab4121/