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TCI Click Chemistry | Greyhound Chromatography

TCI Click Chemistry

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“Click Chemistry” is a term which was first described by K. B. Sharpless of the Scripps Research Institute in 2001 to describe reactions that afford products in high yields and in excellent selectivities by carbon-hetero bond formation reactions. The term “Click” means joining molecular pieces as easily as clicking together the two pieces of a seat belt buckle. In general, the definition of click chemistry is described as follows:

1. give very high chemical yields of desired products

2. combination of readily available simple building blocks

3. generate almost no byproducts

4. simple product isolation by non-chromatographic methods

5. reaction proceeds in water, as well as in organic solvents

 

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